I was asked to write an article on the herbal treatment of Parkinson’s disease for the American Herbalists Guild Journal. Here it is, with a special discussion of the relationship of prions and the leaky gut/leaky brain relationship.
Like most neurological diseases,Parkinson’s is caused by a mesh of genetic, infectious, epigenetic,environmental, dietary, and lifestyle factors that intersect to create a perfect storm. I have been interested in the herbal
treatment of Parkinson’s since I was diagnosed with it eight years ago. This has led me to try a variety of treatments for my clients and myself, from diet and herbs to acupuncture and craniosacral therapy.
Pathophysiology of Parkinson’s Disease
Parkinson’s disease is chronic disorder of the nervous system. It isn’t fatal, but it can cause debilitating symptoms that impact everyday movement and mobility. The cells that produce dopamine are damaged in people with Parkinson’s disease. Dopamine is a neurotransmitter that helps communicate messages between different sections of the brain. Without enough dopamine, …moreContinue reading The Herbal Treatment of Parkinson’s→
DEFENDING HERBALISM, OR NOT
At one point in my herbalist journey I refused to read or listen to anything which criticized my path. Those jerks! What is their problem? Herbs are great! Haven’t they read my blog?!?!?! And then I sought these people out, just to get mysef.
My love of herbal medicines was fragile, like a precious bit of fine China, something I needed to protect and guard. And I felt like I needed to defend my right to use herbs and to make my own health choices, and I was interested in being right.
I would pick out the one point that they got wrong, while ignoring the parts which may have taught me something. Why can’t everyone see my way?!?! How can they possibly not GET this!?!?
But now, I don’t give a rat’s ass.
I have moved through the idea that other people need to believe what I believe. (Mostly.) I actively seek out people who don’t use herbs, and I am interested in why some people dislike them, make other choices or can’t access them.
I have tried things. like actually tried, not just read about them in a book or a magazine.
I have seen examples where herbs and other “alternative” healthcare have not worked, are not the best choice, or are promoted in actively manipulative, confusing or even potentially harmful ways.
And ultimately, I feel less threatened by others who want to prove me wrong. Go ahead. In fact, it would be helpful. I will read your critiques now, and sometimes they are right, sometimes wrong, sometimes both. I feel more confident in my use of plant medicines and my connection with plants, as well as my movement and nutrition choices, but I am always willing to learn more, to dig deeper, to ask questions, even of myself.
And I can see the humor in our humanity, the way we divide ourselves, the way we all form our groups and our paradigms and our dogmas and stick onto them like medicinal leeches. I am this and you are that. It is freeing to unstick myself from the sweaty leg of any one side, any one path.
And as I get older I have more of a grasp of what it means for a person and an idea to mature. I do love the new, fresh, youthful rage-against-the-system energy that innovates and wears hot pink and turns it up and boinks everything that moves, and must yell THIS WORKS in all caps on every herbal forum. Juicy, but fragile. Now I am falling in love with this more mature phase that brushes off others’ hyperbole and panic, lets my actions speak for themselves and commits to just keep walking, outlasting the haters. Well, tries to.
I still want to debate people who disagree with me, respectfully, and I still want to share my love and joy around plant medicines. And, OK, I occasionally still craft long silly arguments in my head. But I am not afraid of the other opinions and approaches anymore. And there are many sides, not just 2, not just for vs against, not just pro vs anti, not just woo vs science, not just tin foil hats vs Big Pharma conspiracies. Maybe, sometimes, they have a point. Or maybe they are reactionary douchebags. Maybe they are just lonely or disconnected, and maybe we can be friends.
As an herbalist for whom tastes of herbs -sweet, sour, salty, spicy (pungent), astringent and bland- imply specific medicinal actions. Bitterness is something that is often confusing because there is a genetic component to the ability to taste – according to 21 and Me I belong to a snip where 80% cannot genetically taste bitterness. (I am in the 20% that can.) The most often confused tastes are sour or pungent. I cannot attribute a pungent herb like horseradish or a sour taste like lemon as “bitter”. Bitter covers tastes like black coffee, radicchio, karela (bitter melon), dandelion greens, black walnut hulls, gentian, angelica or artichoke leaves. There is often a slightly sweet aftertaste to bitterness.
In herbal medicine the largest category of herbs tends to be bitters, which are anti-infective, anti-inflammatory, digestive causing bile to flow and often antiparasite. Herbalist David Winston categorizes bitter herbs as cooling bitters, warming bitters and antiparasite aromatic bitters which are intensely bitter.
There are two basic qualities associated with bitter taste:
According to the five element systematic correspondence, the bitter taste is associated with the heart system. The alkaloids and glycosides commonly found in bitter plants help explain this relationship, as the Chinese heart system corresponds mainly to the nervous system and circulatory system of Western medicine, the two systems most strongly impacted by these types of active constituents.
According to the taste/action dogma, bitter herbs have a cleansing action (removing heat and toxin). The cleansing action of bitters mainly refers to their antimicrobial and anti-inflammatory effects, which are found with alkaloids, glycosides, and flavonoids. The bitter herbs also dry dampness, and this refers mainly to reduction of mucous membrane secretions; we can recognize today that increased mucus secretion is usually secondary to inflammation and infection.
Meals should start or finish with something bitter, be it a salad with bitter greens or an aperitif or digestif drink or an espresso after eating. Fernet Branca and Angostura Bitters are two commercial bitters, but I love Urban Moonshine’s Maple Bitters which come in a handy purse spray. Or you can take a slice of lime in water and bite down on the skin. This will stimulate your bile and stomach acid production. (So-called “acid reflux” in people over 30 is usually a problem of stomach acid being too low to stimulate the closure of the esophageal sphincter.) When the bitter taste stimulates peristalsis it helps relieve constipation and even depression. It helps create the optimum conditions for the gut bacteria as well.
In Chinese Medicine reading the pulse is one of the two key diagnostic methods, tongue diagnosis being the other. We use 3 fingers below each wrist where we can access different depths of the radial artery as it lies over the curved bone. The different positions under each finger have been correlated over the centuries with different organs. We listen to the movement of blood in the blood vessels and note the speed, shape and any rhythmical irregularities coming from the heart or other tissues. We feel the thickness or thinness of the blood vessels, how deeply they lie, how full of blood they are and note their resilience and vitality. And we note the tension of the tissue around the blood vessel. Radio signals communicated between the brain and heart gives information we may not be able to verbalize. It is a deep listening.
Too often we practitioners draw from a pool of similar patients and are not able to experience the vast information potentially read from pulses. Even more infrequent is the pulse experienced at the end of life when many are in hospitals hooked up to machines that may interfere with natural death.
I was fortunate to be able to listen to my father’s pulse as he passed away at home and I thought you might find it interesting. Ever the teacher he would not mind my sharing this with you.
My dad was an 89 year old man in otherwise good health who had leaky heart valves. He had chosen not to get them repaired as it usually involves some mental impairment and he was teaching graduate school classes until last year. So the ability of his heart to support his activities was substantially reduced as the valves were unable to push blood through the heart.
During his last day his pulse was very rapid as his heart was compensating for the low force. Qi could not command blood. The beat started strong then fizzled out as the weak valves could not push the blood. It was regularly irregular but the “fizzle” took a third to a half of the beat. He was so hot he required fanning, but his hands and feet were icy cold. This would be what we call false heat caused by the stagnation of blood due to low qi/ force. The force of the pulse was low but curiously his Kidney pulses were not inordinately weak compared to the others.
As he died his breathing was reduced and it was hard to find what had become a feeble pulse. The pulse got deeper and deeper until it was hidden. His forehead was still hot as was his vertex but the warm area moved up and the cold overtook him. The pulse diminished and he peacefully died.
Reishi is the Japanese name for Ganoderma lucidum, a mushroom known as Ling zhi in Chinese medicine. Similar species are found from the Amazon rain forest to the Arctic and have similar tonic uses. The mushroom is known to be powerful and features in myths about raising warriors from the dead. While it lacks that specific property, the mushroom is used for everything from increasing blood quality to treating cancer. Mycelial extracts done well on wooded substrates have similar to superior healing characteristics to those of the whole mushroom according to mycologist Paul Stamets. Nonetheless the mushroom itself excites users, with its antler or mushroom forms and red shiny surface.
The ganodermas (black G. lucidum, red G. lucidum, G. oregonense, G. tsuga, G. adspersum and G. applanatum) are tonic, immune strengthening, protect against cancer, have anti-tumor properties, calm the spirit, protect and clear heat from the central nervous system, open the heart, lower serum cholesterol and are good for adrenal fatigue and for depression and anxiety. They enter all five zang organs. They have anti-allergic effects, inhibiting histamine production and stabilizing immunoglobulin levels. They lower blood pressure, are antioxidant, antiviral and antibacterial. Combining with astragalus, atractylodes and Ren shen increase phagocytosis, promote immune globulin formation, promote lymphocyte transformation, and induce the generation of interferon. Chinese mountain climbers use Ling zhi to alleviate altitude sickness by oxygenating the blood.
I learned from a Thai doctor with a cancer practice, Santi Rosswong, to make a water decoction of Ganoderma lucidum (Ling zhi) with 10% cordyceps [Dong chong xia cao] for stamina. But since the polysaccharides in ganoderma are quite long, it has been shown to be more effective if the decoction is taken with not less than 500 mg of vitamin C, and 5 mg of folic acid each time. (The vitamin C is based upon Japanese research by Morishige and the folic acid is based upon Santi’s clinical experience.) Take several tablespoons (or more) every three hours. The most important dose is just before retiring, which should be larger. Take the folic acid and vitamin C with each dose.
There are two types of tinctures. One uses a concentrated decoction and adds alcohol to stabilize it. When I make it, I learned from Chris Hobbs to shoot for 25% alcohol to protect the polysaccharides, to ensure that I got between 22% and 28%, the lower number for spoilage and the upper number being a maximum for the polysaccharide protection. This appears to be the best formulation for immune system effects. The other way is to use a high alcohol formation to get the triperetenes, but I understand that this destroys the polysaccharides and differs significantly from the constituents extracted in traditional uses or from powdered extracts. It may have stronger CNS effects however. I know several herbalists who make a high alcohol tincture and add it to the subsequently decocted marc to get the best of both (and they understand that the high alcohol just makes the polysaccharides clump together on the side of the tincturing vessel but does not destroy them). There is not a consensus.
Ling zhi has various steroidal compounds, long chain polysaccharides, bitter triperetenes such as ganodermic acid and some volatile oils. Unlike Echinacea which activates macrophages, ganoderma is not believed to stimulate the immune system directly. It is probably an immune regulator rather than an immune stimulant. Ling zhi mushrooms get to the bone marrow and induce the marrow to put on more nucleated marrow cell mass, according to Jia. The marrow then increases B-cell production, which in turn increases antibodies. The DNA and RNA made in the bone marrow increases production of lymphocytes. This very deep immune nourishing means that it may be appropriate for AIDS patients although the patient should not suffer from undue dampness. For cancer therapy, combined with other fu zheng herbs, Ling zhi can be quite useful, even for patients undergoing chemo and radiation. Hobbs recommends low dose decocted ganoderma with cinnamon bark and orange peel as a tonic drink (for those not suffering from undue dampness) and I find that preparation, with roasted dandelion or chicory, combines well with coffee, helping neutralize coffee’s negative effects.
(Karen S Vaughan, adapted from Chinese Herbal Academy post 8-26-2000)
I’m thinking today of all those who have lost loved ones, who honor them with grace, and whose resilience represents triumph and hope. The sh..t hit the fan in a way that knocked us sideways. Watching the plume from the roof. Breathing in air full of construction debris and dead bodies for weeks. Yet this was a seminal time for recovery 14 years ago. Spiritual outreach, acupuncture outreach especially to the rescue workers who dug through piles of carcinogenic debris looking for body parts, Recovery clinics throughout lower Manhattan. Working on rescue workers who appeared in the Michael Moore film Sicko because they couldn’t get government funds for their 9-11 related illnesses, despite the promises. The resilience of a city that went from PTSD to recovery. We honor the memories and plan for a new future.
More people are poor. Many lost all they had. Others used the occasion to amass fortunes and cut out jobs for a few more cents on the dollar. Ecological and social disaster go hand in hand. The clues are all around us. We have to change. Now the big question is, what is the first step to getting us where we want to be, where this kind of thing isn’t happening due to things that we might be able to prevent.
I get a lot of prepper stuff in my emails, some useful and some fearmongering. (One claimed he had to shelter his small blond niece from marauding hordes in the Rockaways after Hurricane Sandy- I know the area and it didn’t happen but probably sold copies of his ebook.) Those of us in NYC face WTSHTF situations frequently: 9-11, Sandy, blackouts, terrorist near misses, epidemic dangers, loss of food stores in damaged areas even sweeps of tens of thousands of people into government detention. Usually it brings out the best in people. We pull together for a few days or weeks. And we bounce back.
There will certainly more disasters as weather patterns change. My off the grid in the woods friends got chased out by forest fires this year and the fires covered many states and Canadian provinces. First Nation’s people find that fresh moose meat is suddenly green, if they can find moose even miles distant from the tar sands destruction that poisoned land and water. West coast starfish are turning into blobs instead of stars. The big earthquake could hit Oregon, Washington and BC with folded earth and tsunamis. New Orleans hasn’t fully recovered from the Katrina floods in 10 years and more hurricanes and underconstructed levees can be expected. Deformities and low birth rates affect elk, birds and bears which affect Native food chains. Crops are dying or in lowered production. Glaciers providing water in Bolivia are gone and those in parts of the Himalayas which supply water to India and Bangladesh are close to missing. The population of Syria suffered from drought conditions before migration and civil unrest broke out and now great populations are fleeing for their lives. Populations move with increased desertification and civil unrest grows. Diseases will spread. It isn’t just “them,” it will touch all of us.
This is the time for social and physical preparation. Put aside some cash, a little food, water, medicine, batteries, fuel and first aid supplies then reach out to your community. Join a civic help group or start one yourself. You can work with your neighbors to be prepared and to identify skills and locations for clinics, sanitation and communication when various disasters strike.
In a disaster you can bring food to the elderly, get supplies to housebound neighbors, bandage wounds, help direct traffic and do all kind of things. After Sandy my congregation made meals for over 100,000 including for elders in upper floors of high rise buildings. I worked in a makeshift acupuncture clinic giving trauma treatments after Katrina and Sandy. We worked on the rescue workers at the Convention Center after 9-11.
Work with your political groups (Occupy gave NYC far more assistance than the Red Cross!) Get your church, mosque or synagogue to organize help for whatever is going down, Learn first aid, CPR, defense techniques and how to listen. Save your fear for after the crisis passes so you can be of assistance. We are connected and we can get through things.
As many of you know I had a stem cell implant in January at StemGenex in La Jolla California. I had been somewhat discouraged by the effect on my Parkinson’s disease but two different people in the past week have spontaneously remarked that my tremors have reduced. The tremors have spread to the other side, but are less intense. So it may well be that I am not the best judge- I only pay attention when the tremors are active.
I want to say right off that even if I’d had no effects whatsoever from the stem cell implant that valuable information would be derived from the study. We need to learn who responds and who does not. There are considerations of the effects on insulin resistance and gut bacteria, as well as vagus nerve stimulation that affect the success of stem cell implants. We need more experimentation on how and where to administer the cells and what activities will impact their proliferation. (Too bad for nonresponding participants who pay out of pocket but good for science.)
It is true that I haven’t had the dramatic changes that I expected. And I might have done better with stem cells taken from the cord blood of a newborn rather than my own adipose (fat) cells. When you are fat, the fat cells can be hypoxic and less vital. One doctor I spoke with in Mexico said he prefers cord blood because the stem cells are more active, even if there are considerably fewer of them. If you are heavy and are considering stem cell implants you might consider using cord blood. Cord blood is not available in the US, but there are reputable firms outside of the country.
Do I think losing weight prior to a stem cell implant might have helped? Only with a few years lead time and lots of detoxification. The problem is that fat stores toxins to protect the body from the harm they can cause. I have tested high for lead, strontium, DDE and other endocrine-disrupting compounds. Weight loss can dump toxins into the blood stream and tissues as fat cells are broken down or deflated, which is why I have gotten sick every single time I lost weight, even slowly. I did a course of herbal detox and DMPS, EDTA, and Olestra (1) chelation prior to the stem cell implant to reduce toxins but stopped a month before the implant to let my body normalize. Chelation cannot be done after the implant until the cells have finished multiplying.
A friend tells me that our neighbor is still experiencing improvements 2 years after his stem cell implant – and it took a while to build up. He saw the greatest improvement after he started getting deep massage and using a vibration platform late in the first year. So there is still hope. It has been only 6 months. One woman with MS who was going through the implant with me for the third time said that the first time there was no change until 6 months and suddenly she was able to raise her legs two feet instead of two inches. Pazienza, Karen!
I was advised by a colleague with Parkinson’s to get a vibration platform to increase the stem cell activation and to reduce Parkinson’s symptoms. I used one last week while visiting my parents and it definitely activates qi and blood, affecting not only circulation but eliciting a strong stretch-reflex contraction in muscle fibers. It is a very efficient anaerobic form of resistance training and they claim that 10 minutes of platform exercise is like 60 minutes of regular exercise. Vibration platforms for the home run between $200- $6000. While the pure platforms without handholds look like they give a stronger vibration and certainly fit better in a NYC apartment, the design looks risky for someone with Parkinson’s. The $250 Confidence Fitness machine has over 700 five star reviews on Amazon. I am saving up for it now.
Ronald J. Jandacek, James E. Heubi, Donna D. Buckley, Jane C. Khoury, Wayman E. Turner, Andreas Sjödin, James R. Olson, Christie Shelton, Kim Helms, Tina D. Bailey, Shirley Carter, Patrick Tso, Marian Pavuk.Reduction of the body burden of PCBs and DDE by dietary intervention in a randomized trial. The Journal of Nutritional Biochemistry, 2014; 25 (4): 483 DOI: 10.1016/j.jnutbio.2014.01.002
There are many reasons you might have spasms and the hard, painful clenching of contracted muscle can hurt enough to wake you up in pain. What you do is not the same for everyone
Overuse or overtraining can cause your body to go into spasm, especially if a nerve is involved. This serves two purposes: it gives you temporary if somewhat distorted support and gets you to stop what you are doing. Use an analgesic that reduces pain and moves blood like aspirin or Dr. Christopher’s Antispasmodic formula or a Chinese martial arts dit dat jiao trauma formula.
A dit dat jiao is a liniment or topical tincture made up of herbs that increase circulation (including microcirculation of the capillaries), release the muscle layer and relieve pain. If there is a lot of redness and swelling a cooling effect can be added with mint or menthol the first day since this relieves inflammation without the bad effects of ice.
There has been controversy about using ice when a spasm first starts. Don’t. In Chinese medicine ice has always been proscribed because it drives the pain in deeper while giving surface relief. Blood can congeal (clot) deep inside, blocking the circulation necessary to nourish the tissue, so it takes longer to heal the spasm. Heat both increases circulation and relaxes the spasm. Western medicine has finally caught up with Chinese medicine, although some trainers and doctors have not yet caught up with the research.
Related to overuse is poor functional posture which over time stresses some muscles and produces weakness in others that ought to work together. An example of this is “computer neck” where the SCM, trapezius and other neck muscles become rigid because the head is held too far forward. Yoga, Pilates and MELT classes can work on correcting posture while structural integration can separate conjoined fascia so that muscles can work independently. While nutrients and herbs can reduce pain it is important to improve the functional posture to eliminate the cause.
Lack of magnesium which is an endemic condition in America can also affect cramping. Dietary magnesium is down 50% in the last 30 years as soil has been depleted by industrial farming and erosion. Oral magnesium is difficult to absorb and I have been able to reach good testable levels using Jigsaw Sustained Release capsules twice a day plus topical magnesium oil from the ancient Zechstein inland sea. I also do periodic soaks in Epsom salts or Magnesium Chloride salts.
Lack of iron is also a cause of spasmodic leg shaking but should not be supplemented unless blood tests low. The Chinese cure would be to eat liver for such Liver Wind conditions.
The widespread use of statins for cholesterol has led to a wholesale depletion in Ubiquinone (Coenzyme Q10,) the body’s natural antioxidant. While statins have tested as useful for males who have had heart attacks, the usefulness for anyone else is unclear. Cholesterol is the body’s natural bandage for inflamed arteries and is the building block of steroid hormones and brain tissue, so there are good reasons to not lower it. Statin use is known to frequently lead to muscle pain and more rarely rhabdomyolysis, a severe condition which affects the muscles. The most common signs and symptoms of rhabdomyolysis include:
Severe muscle aching throughout the entire body
Dark or cola-colored urine
The higher the dose of statins, the higher the risk of rhabdomyolysis becomes. The risk also increases when taken in combination with certain drugs.
Low B vitamins can also cause spasms. Try methylfolate instead of folic acid and methylcobalamin instead of normal B12, particularly if you know you have the MTHFR gene snip. (If you don’t know I’d take these forms anyway.) Low doses three times a day are best and take a methylated B complex.
Although it does not seem intuitive, eating gluten can cause muscle and joint pains. Once the inflammatory proteins get past a leaky gut they circulate with the blood all over the body, causing pain
Diseases like Parkinson’s and Essential tremor can cause hard spasms due to the continual shaking. Work on increasing liposomal glutathione, CoQ10, Vitamin C and Folate as well as a full component of minerals, detoxification and exercise.
Body work is very important. Deep massage, myofascial work, bonesetting tuina or chiropractic can make a great impact on nerve-related or muscle work.
Acupuncture is very good for spasms, on both a local and distal level. It is not necessary to needle directly into a spasm, but if the spasm is not too hard or sensitive,
local needling can increase circulation into the spasm. But needling on the opposite side, along the meridian or into special points can signal the brain to release muscles or endorphins.
If you have food allergies, diabetes, are gluten sensitive or are eating paleo you may need to bring your own food to eat in a way that supports your health. One of my teachers in acupuncture school developed the concept of “cloak food’, food that fits in the pockets of your cloak. It should be small, light weight and substitute for your dietary pitfalls.
For instance if you are prone to joining in for a soda, a packet of Eboost, Wellness Fizz, Emergen-C or Calm can add flavor and fizz to your water, not to mention some awesome herbs, minerals and vitamins.
Nuts, pumpkin seeds or sunflower seeds make a good low carb snack for the afternoon blahs. Add some cacao nibs or dried goji fruit for a healthy trail mix that will beat out anything the vending machine has to offer.
Shake packets can store easily in your pocket, purse or desk drawer and a pint sized jar with a lid will substitute for a no-fuss blender. If you make up your own in baggies you can add superfood powders.
More suited to a backpack or briefcase, a few sheets of nori make a gluten-free, mineral rich substitute for a wrap or sliced bread. I carry around a pack in my backpack. Place a few slices of roast beef or spoons of humus in the center and roll it up. (It gets soft if you do it in advance.) If you are not too sensitive, order a sandwich, ditch the bread and put the inside in the nori. No one said only sushi should be wrapped in nori!
If you need a non-dairy milk in your coffee, get an individual sized aseptic pack of coconut milk or whatever you drink. I will carry the ones with a screw cap in my purse for the day or leave the packs with straws in my office refrigerator. They stay fresh a bit longer than dairy milk after opening.
Boiled eggs can survive for a week without refrigeration and you can bring a salt pack from the deli or learn to love the plain flavor. Jerky, especially salmon jerky also provides a protein-rich snack.
Fruit that is not too tender is also easy to carry. If you need fewer carbs, slices of zucchini, celery, fennel, baby carrots or a small endive can fit in a ziplock baggie. The main idea is that you think ahead to protect your dietary needs while having a few dry alternatives if you forget.
Don’t forget your water bottle. I like to make overnight infusions, very strong teas, of nettles or oatstraw. (How to at the link.) 2
In the morning I strain them out and put my day’s dose in my water bottle to sip during the day. Don’t worry, these will hydrate you as well as water and will add a phytonutrient benefit.
Medicinal mushrooms are in great demand because of their adaptogenic effects and their actions against cancer. They improve the immune system, balance the hormones of the HPA axis, are anti-inflammatory, antioxidant, tonify the heart, protect the liver and soothe the nerves.
Taking them in an effective way is not so easy. Eating medicinal mushrooms like shitake or maitake doesn’t release the medicinal value (except perhaps the Vitamin D.)
If you want to take them as a tea (decoction) you need to simmer them for at least an hour to separate the medicine from the chitin. (Yes mushrooms have chitin, like sea shells.) This is the traditional way used in Chinese medicine. Chris Hobbs suggests keeping a pot warm on the back burner at all times, periodically adding water, astragalus, cinnamon and orange peel so you only need to make it every few weeks. Cooking herbs daily can be a bit much and decoctions only last a few days in the refrigerator but it works and I have used this kind of decoction to make ganoderma coffee.
Tinctures or liquid extracts are portable, let you taste them which makes them more effective than capsules, but are not simple to make. You can’t just soak the mushrooms, either fresh or dried in alcohol. The chitin still locks up the medicine. The most important fractions of the medicine are polysaccharides like beta-Glucens or Mannogalactoglucan which don’t survive even medium levels of alcohol.
Polysaccharides clump together when exposed to alcohol and become inert. Below 30% the alcohol is not strong enough to percipitate out the polysaccharides. The triterpenes like Ganoderic Acid in reishi are also medicinally important and require a high alcohol percentage to be extracted. So to get the most medicine, you need to follow a two step process and combine them with 25-20% alcohol to make a liquid extract.
For 250 grams, slightly over 1/2 pound of mushrooms you will want to make 1 1/4 liters of liquid extract. It will be 30% grain alcohol or 375 ml and 875 ml of decoction.
The first stage is to decoct the the given weight of dried mushrooms in water. You need to simmer below a boil for at least an hour after they rehydrate, longer is better. The bigger the mushroom chunks the longer- Chinese herbal pharmacies sell reishi in thin slices which I usually spin in the Vitamix., but before I had access to those I would chunk as small as possible then run in the Vitamix mid cooking when the mushroom was a little softer. Chaga can be obtained through Mainley Chaga in a coffee grind (but for the medicine decoct it- don’t just run through your coffee maker!) If you wildcraft, slice thinly before the mushroom dries and dry it gill side up in the sun for maximum Vitamin D.
Start with your ground dry mushrooms. Cover with water and let it absorb. Add more water so the mushroom chunks can freely swim. Cover and simmer for an hour or overnight. Strain and squeeze out, measure the decoction in a Pyrex container to see if you have enough, 875 ml in this example, and cook down the decoction to the quantity you need or top up with water. Freeze until the tincture is ready. (Squeeze it out really well.)
Take the strained out marc (which has had most polysaccharides removed) and add Everclear/ grain alcohol to get the triterpenes. For 250 gr mushrooms use 275 mililiters of Everclear. (Because the mushroom pieces will have absorbed water, you need less alcohol than if you were to tincture in alcohol directly and lose the absorbed alcohol.) Store in a dark place for 1-3 months, shaking perodically and strain out really well, squeezing the spongy marc. Mix the finished tincture with the defrosted decoction very slowly, stirring well to get a 30% alcohol level.
(Some just stabilize the decoction with plain 95% grain alcohol but it won’t be as strong. You can also use two batches of mushrooms, one for alcohol and one for decoction in water. You need 7 parts decoction to 3 parts Everclear tincture. It will cost more and you will need more Everclear but it is convenient.)
You can also find Chinese dried granules to rehydrate with warm water, but it won’t have the triterpenes. These can be combined with other Chinese herbs in a formula, although I find granule formulas somewhat less effective than raw herb formulas. (They are convenient however.) And Mushroom Harvest makes a well-done steamed granule that you can put into smoothies. If you purchase tinctures call the company that makes them and find out how they make the tincture- there is a lot of inert or very weak medicinal mushroom tincture out there. You can do better by following these instructions.
<< Does anyone routinely use any calming herbs often enough to know if they are safe for nursing mothers? I was thinking of Valerian, hops and passionflower for my sister’s second child (the oldest still wakes during the night)…>>
The time after giving birth is normally somewhat anxiety producing. A new mother who typically had interrupted sleep follows what might be the most physically challenging event of her life with insufficient sleep and the overwhelming responsibility of a helpless new baby (particularly if the baby has colic. )
Catnip might work as well as valerian and is definitely fine for the baby. In fact you can give it to the baby directly. Valerian is listed as safe during lactation, but make sure she gets fresh root tincture rather than dried capsules because the dried herb can be stimulating instead of sedative and calming. I prefer teas to tinctures for breastfeeding moms because fluid keeps up the milk supply, which makes catnip, which can be dried, preferable.
Mints are fine, fennel is good for the milk, fenugreek is too but can make you fertile sooner, astragalus is good if you need an immune booster. Garlic is good although some babies don’t like the way it makes the milk taste- but others adore it. Oat straw is a nourishing nervine. Carrot juice will help, especially if anxiety makes your milk supplies lag.
A new mother can experience anxiety if she does not know what herbs are safe for other conditions she may experience during the breastfeeding period. Other herbs listed as safe during lactation are:
First off I would see that she gets ton of liquids. Catnip tea is especially good for calming and colic, and if the mother drinks it, her milk will reflect it. A quart per day is not unreasonable. Better yet, she could make an overnight infusion which contains 1/2 ounce oatstraw with heads (avena sativa) and 1/2 oz. catnip, put in a quart jar, pour on boiling water, cap and strain in the morning. It is easy- she can boil the water while she is brushing her teeth and it will help protect her bones and build the child’s. It is also a nutritive nervine.
Milk production is primarily related to the amount of liquid consumed, the suckling of the child which stimulates milk and stress. If she has other children and a non-sleeper, she should be getting help during the day so she can nap whenever the baby does. It is worth the money- and not just for milk production!
Milk production is normally cyclic and usually reflects the baby’s hunger patterns, which may change. They seem to go on milk binges just before growth spurts and when teething- and the teething pain seems worse when the teeth are cutting through the internal gum layers, long before they emerge. Probably not the issue now, but I know of two babies who were born with teeth, so you never know. Having a bit extra breast milk is good in a pinch (and a caregiver can give it to the baby when the mother is exhausted and needs a nap or a break.) Airplane trips, as an aside, are great times to pump extra milk because the air pressure makes it easier- so if she has any trips coming up she can bring a pump and cooler. 😉 Just make sure that the milk is NOT heated in a microwave because it kills off the antibodies, is hard to digest and the baby will not thrive.
When the baby is a bit older she can give it catnip tea as well, by bottle. I’d wait until the second month, and make sure that it does not displace the milk consumption. 1/2 bottle per day under 6 months and a bottle after, in divided doses, as required. The oatstraw/catnip infusion would be particularly good.
The mother can take fennel, fenugreek or mint teas as well. Mothers Milk tea by Traditional Medicinals is good. She should watch her diet (broccoli, onions and other foods high in sulfur are common foods to cause colic but again depends in the baby.)
I would also encourage the mother to sleep with the baby when she feels anxious or overwhelmed. The baby is more likely to sleep, less likely to awaken and can learn to nurse while the mother sleeps. (He’ll even learn to help himself after a few months.) I firmly believe that it makes it much easier on the family if the parents take the baby to bed. Everyone sleeps better, there are fewer SIDS deaths (unless she sleeps with him in a waterbed), the father gets to cuddle more than usual and the baby feels more secure. They do outgrow it and the parents usually kick them out when they insist upon sleeping sideways.
If she hasn’t read them lately, the La Leche League has two excellent books “The Womanly Art of Breastfeeding” and “The Family Bed”. The information is not just basic stuff, and bears re-reading if it has been a few years since we usually remember what applied to the first child if it was read then. La Leche can give her advice and provide lactation counselors who do more than help make sure there is enough milk.
Note: The list of safe herbs probably derives from one developed by herbalist Amanda McQuade. I have been using and adapting it for years and am no longer certain of its provenance.
Recently the press was transfixed when NY State Attorney General Eric Schneiderman’s office announced that the vast majority of herbal supplements tested by the AG’s office had none of the herbs claimed. This followed a Canadian Guelph University study from the developers of a novel DNA testing process that claimed a huge percent of herbs tested were bogus. That study was so poorly done that the American Botanical Council asked for it to be retracted. Their title said it all:
Science Group Says Article on DNA Barcode Analysis of Herbs Is Flawed, Contains Errors, Creates Confusion, and Should Be Retracted: Methodological Flaws, Statistical Inconsistencies, Taxonomic Confusion, and Unreliable Conclusions Require Paper in BMC Medicine to be Corrected, Revised, and Re-peer-reviewed
Nonetheless the specter of a relatively inexpensive new test in an industry everyone assumes is unregulated was irresistible to the AGs office (and besides everyone knows DNA is scientific!) This new DNA barcode test is different from forensic DNA tests which is what people think of when they hear “DNA test.” Now GNC has signed a premature consent agreement and the AG’s offices in 14 states are planning to follow suit based on technically misleading testing.
As a clinical herbalist for over 25 years and a professor of herbal medicine I need to point out that the press has given a free ride to the validity of new DNA barcode testing which purported to show that 79% of herbs from Target, GNC, Walgreens and Wallmart were adulterated or missing the herb claimed. The high figure should have given the AG’s office pause. Verification including microscopy and validated chemical test methods, like those found in official pharmacopeias for these seven herbs, should have been conducted to confirm the DNA findings.
When the initial 2013 Canadian DNA barcode study came out it was clear that it was oriented to the sales of a testing method and had poor application to prepared herbs. DNA barcoding is less expensive than traditional herbal tests and that of course would be a great new market for the test developers. Raw herbs before extraction can be identified by DNA. It has proven itself with foods where whole plant products are being tested. But the test only tests the presence of DNA. Unless I am growing herbs, the least useful compound is DNA: instead I want to extract the medicinal secondary metabolites, the minerals, polysaccharides, polyphenols, sesqueterpenes and flavonoids.
A typical Chinese formula has 7-9 grams per herb and 5-9 herbs, so say has 50 grams of herbs daily. You would need at least 20 large 400 mg pills- too much, which is why herbs are extracted to find their most medicinally useful components. DNA isn’t one of those and it is usually degraded by extraction. However there is a need to add something like rice flour to keep the powdered extracts from clumping and that doesn’t need to be extracted, so its DNA is present. The DNA barcode test doesn’t test concentration so it looks like the herbal capsule is free of the herb and adulterated when, in fact, it is properly made.
Now encapsulated herbs are perhaps the least effective form since you can’t taste them. (Taste and smell are not merely aesthetic experiences- they engage body feedback systems.) Powders can oxidize rapidly. I wouldn’t buy my herbs from Target, Walmart, Walgreens or GNC. I want higher quality. But it begs credibility that 79% of products were free of the herbs claimed. You can visit wholesale herb markets to see the tonnage of herbs at reasonable prices. GNC is in the business of selling herbs and they need to have a certain level of quality (if only because people like me will bite into the capsules and can taste whether the herb is present.)
So it was not accurate to say that 79% of supplements lacked the herbs claimed, instead 79% did not have DNA present. It might have other medicinally useful constituents from the herb in question, and in fact subsequent industry-standard testing found herbs in all samples. It was not accurate to assume there was substantial adulteration, only that excipients were usually used. Some 90% of herbs are sold in extract form, unlike the foods that work with DNA barcoding.
There is a need for quality control, especially in the bodybuilding and weight-lifting sectors of the industry where ConsumerLab has identified real problems. I do use suppliers of international herbs who use HPLC and heavy metal testing, but I also purchase whole herbs directly from US growers I know, where I can taste and smell the herbs and make my own extracts. The American Botanical Council has been in the forefront of protecting against adulteration, intentional or accidental. The ABC-AHP-NCNPR Botanical Adulterants Program, is being conducted by ABC with the nonprofit American Herbal Pharmacopoeia (AHP) and the NCNPR, a FDA Center of Excellence lab at the University of Mississippi.
GNC couldn’t afford a shadow over their business so signed the consent requirement. They will have ample evidence they used the herbs claimed but are likely to miss the DNA barcoding target unless they add powdered herb to the excipient. But the spotlight will be off by then. By all means make major retailers stand behind their herbs, but do not enshrine a novel DNA test just because it is cheap.
Trying to assess changes in an intermittent disease is not easy and just this experience has given me a great appreciation for the difficulty in developing measuring yardsticks that researchers face. For instance Parkinson’s tremors are intermittent, happening mostly when I am resting, stressed or overtired. I rarely have them while needling but they come on while riding the subway or just as I drop off to sleep. I suppose that one could invent a wrist monitor that would measure tremors per day and perhaps group them, but I have to rely on memory to fill out the Parkinson’s questionnaire, and that is not exactly reliable. Still people around me tell me that tremors are reduced. Stamina is up too- also hard for me to quantify but I wasn’t walking up to the park before or along boardwalks as I did in St. Petersburg between hyperbaric treatments.
Now some people show evidence of change right away- like the Canadian hockey coach I wrote about- and others may see nothing for 6 months. I seem to be mostly in the delayed category. It has after all been only 2 1/2 months, but this is an interim report.
I had been haunted by the size of the syringe of unused stem cells that was leftover and extracted from the IV when my small veins had given out. After consulting with StemGenex they pointed out that of the 600 billion stem cells extracted, 99% had been used. Those in the IV were diluted with platelet rich plasma, unlike those directly injected. It looked like more than 1% though. I still wish they had found a second IV site, but at least I got most of the cells and more than average.
I saw some immediate improvement in my foot but it didn’t stand up to reinjury from the deformity. The tremors are down and my stamina is up, both of which are significant. I don’t type as many extra symbols when I use my laptop and that makes writing easier. And my win rate for solitaire which is a proxy for both brain function and manual dexterity is up by 1%. I will have bloodwork and eye test results later.
Anyway, I thank all of you who helped me with the stem cell implant and after care. I’ll keep you up to date as the cells proliferate and things develop.
And if you would be so kind as to continue with support: Help a Healer
I was fortunate enough to be provided access to a hyperbaric oxygen chamber, thanks to the generosity of Robert Linde and his very helpful staff. Acupuncture & Herbal Therapies of St. Petersburg has an extraordinary array of services from TCM and CCM acupuncture, herbal medicine, NAET, hyperbaric oxygen, massage, classes in qigong, herbal medicine and an acupuncture externship. They even have a functional medicine doctor with a nutritional IV lounge and access to tests we can’t get in the medically backward state of New York. The whole experience has been significantly helpful and if you need services in St. Pete I highly recommend their services.
Of the three hyperbaric chambers I have used, I like this one the best. Unlike the first soft chamber it was white so I could see to read and it was tall enough to sit crosslegged. Unlike the clear 100% oxygen chamber I could sit up, move around and bring in electronics like my iPad for music or internet and my cell phone, They also gave me a walkie talkie so I could radio for help (like cooling the air if it got too hot) or to get out. The mask would get hot but I hit upon removing the tube and sticking it directly in my mouth to get the oxygen. That combined with frequent checks by the helpful staff and my coconut water (with that anxiety-quelling vanilla bean) during the depressurization stopped the anxiety. And the ear seeds Bob applied didn’t hurt!
Even if the 100% oxygen clear chambers might appear to be stronger, the discomfort reduces respiration, and that minimizes how much oxygen gets into the blood.
I am told that pressure beyond 2 atmospheres as in the clear chambers doesn’t greatly add to effectiveness. There might be an advantage to using the 100% oxygen in the entire chamber for nonhealing sores, but even those respond to breathing it in through the mask, So of all the hyperbaric chambers I used, I liked this best and felt better with the treatments,
As I wrote previously hyperbaric oxygen helps the stem cells proliferate after insertion and it looks like the mechanism is an increase in Nitric oxide.Dr. Marshall Ravden, the stem cell implant surgeon gave me a prescription for 40 sessions of hyperbaric oxygen, necessarily taken over a narrow period of time to consolidate the stem cell benefits. They suggested renting or purchasing a unit, but I could just see telling Larry that our apartment dining room was to be taken over by a 7’x4′ diameter inflated hyperbaric chamber and that the cat would need to be relegated to the bedroom! Not gonna happen.
The good 100% oxygen chambers almost all seemed to be in hospitals where they only took insurance (at $2000 a pop!) but I found one in Queens and another, New Focus Hyperbaric in Great Neck where a GroupOn special was going on. The chamber, shown above, was clear, had a television to distract me, was not quite as large as I had hoped but had a full-time compassionate attendant so I wouldn’t be deserted as happened in the Manhattan soft chamber. Sessions last about 2 hours.
Now I occasionally suffer from claustrophobia in airplanes, but it is easily remedied by sitting in an aisle seat so I can walk around and I use Stand-Up MRI if I need radiology, so it rarely happens to bother me. I used to scuba dive so I knew what pressure felt like and how to clear my ears. So I got my required chest X-ray and was cleared by the resident neurologist. But the second trip in threw me into a tizzy: the bottom of my foot itched, it was in hard spasm and annoyingly Bobby Jindall was being endlessly interviewed on CNN. I had the attendant talk me down a few times then came out to relax before going in again. I went in for another try but didn’t spend much time at full pressure. The next day I had a panic attack on the subway which I have been riding without incident for 35 years so cancelled my session. I felt claustrophobic lying in bed surrounded by my comforter or when listening to dissonant New Music on NPR- the claustrophobia was leaking into my life. (At least it gives me more insight into what patients are going through!) I asked for suggestions on Facebook and my wonderful friends gave suggestions in troves.
The suggestions ran the gamut from sedatives to acupuncture treatments, homeopathics to cell-level visualizations, prayers to reiki, breathing patterns to a reminder that this was a First World Problem I was lucky to have . A few people suggested that I was repressing something -honestly I think it is just that I fill up a chamber more than a smaller person and can move around less. Three people jumped in instantly with the words from Frank Herbert’s Litany of Fear, when I requested it. I did EFT tapping and bled my UB luo point, inserted needles at LI2 and H5, did breathing exercises gave myself a shot of a skullcap formula and liberally breathed in essential oil of lavender. I also requested a prescription for a sedative and asked for puppies and kittens instead of the news on TV. Animal Planet was unaccountably playing the World’s Filthiest Jobs that day which included scraping hides at a tannery, so that didn’t work. This time I spent a half hour at full pressure plus 15 minutes of pressurization. The attendant decided to lower the wedge and ditch the knee pillow so I would have more room next time. And he cleared me to bring in a sippy cup which I filled with coconut water and a vanilla bean found to decrease claustrophobia in a German study,
And the sedatives, with more space, made the difference. I still reminded myself that it was a First World Problem and tried chants, prayers and breathing patterns. I whistled songs. I sipped. And I relaxed. I might not be a pill person but I need the oxygen more than I need to be an herbal purist. It has worked twice.
For most of my life my blood pressure has been on the low side of normal. Considering that fat people are told that this is desirable, I was never cautioned by a doctor that I might want my blood pressure at the higher end. But several things caused me to wonder whether this conventional wisdom was valid.
When I was in college and stressed, I assumed that stress translated to hypertension and took a physical education class based on the ideas of Hans Selye using breathing to lower my blood pressure, which it did. I realized that I always felt worse after class, dragging myself home and feeling sleepy for hours.
As a budding herbalist I learned that European doctors often diagnose and treat low blood pressure whereas US physicians rarely do. I find no difference in official guidelines today where 90/60 is the accepted lower level except for trained athletes in both locales. Unless one is in shock, fainting or frequently dizzy there is no official concern about low or borderline low blood pressure. Still American doctors are more concerned about hypertension than hypotension.
When I was doing my EMT training on oxygen therapy it occurred to me that many of the symptoms I felt were symptoms associated with oxygen hunger. Was it possible that with my borderline low blood pressure, blood wasn’t delivering enough oxygen to my brain? After all blood needed to get through the contracted muscles and herniated discs in my neck. This was reinforced by my experience in acupuncture class where walking briskly around the block during break kept me more alert than going across the street for hot coffee.
I propose that borderline low blood pressure which is currently classified as “asymptomatic” often leads to low brain oxygen, brain fog, cold and tingling extremities, and what we call in Chinese medicine yang deficiency. It probably interferes in the desire to exercise, the levels of possible exercise and the benefits of exercising. Chances are that it is a factor in at least some patterns of obesity.
Look for low capillary refill when you press on a fingernail. pulse oxymeter readings below 95%, cold hands and feet, brain fog, and poor memory.
Then there is the common sense issue. Obesity adds miles of blood vessels. For every ten pounds of fat gained, your heart has to pump blood through an additional 35 miles of blood vessels, and ten pounds of muscle has about 65 miles. So it makes sense that some degree of elevated blood pressure might be needed to push nutrient and oxygenated blood through them. Shouldn’t a 250 pound person have more pressure than a 150 pound person to get through an extra 550 miles of blood vessels?
Note I am not suggesting that the extra burden of pumping through blood vessels isn’t hard on the heart or kidneys. The negative cardiovascular effects of hypertension are well known. What is less understood is the adverse effects of low blood circulation on the brain with lowered delivery of oxygen and other blood-borne nutrients. In the obese, elevated blood pressure may be the body’s way of compensating for oxygenating extra mileage.
There is strong evidence to support treating hypertensive persons aged 60 years or older to a BP goal of less than 150/90 mm Hg and hypertensive persons 30 through 59 years of age to a diastolic goal of less than 90 mm Hg; however, there is insufficient evidence in hypertensive persons younger than 60 years for a systolic goal, or in those younger than 30 years for a diastolic goal, so the panel recommends a BP of less than 140/90 mm Hg for those groups based on expert opinion.
Still two persons of the same age might have different optimal blood pressures. One who demonstrates what Chinese medicine calls Heat- inflammation, red skin, rapid pulse and a scarlet tongue probably needs blood pressure controlled more vigorously than one who demonstrates Cold signs like cold extremities, a slow pulse, a pale tongue and pale skin.
I also need to point out that too-small blood-pressure cuffs in an increasingly obese population will tend to overdiagnose hypertension and will engender treatment when not needed. IOW ask for a large cuff if you are heavy or you may make things worse.
This doesn’t mean that anything goes. You don’t want to stroke out. I am talking about expanding the marginal limits of what is acceptable in blood pressure standards at both ends. In other words blood pressure should be high enough to circulate blood trough the tissue, and when it gets higher, an individualized consideration of how high is acceptable should be undertaken.
How long does it take before I will see the results of the stem cells? The short answer is that it varies considerably, as stem cell proliferation and concentration increases.
One woman in my group was so pleased with the turnaround in her 30 year MS that she came back for more, In her first treatment she had absolutely no improvement for 6 months, when all of a sudden she could raise her leg two feet instead of two inches. She subsequently went from not being able to turn over in bed to being able to drive herself to the gym and work out and she has retained her improvements for several years. But she went through the treatment with another woman with longstanding MS whose improvements mostly happened the first month.
So far my improvements are subtle. My foot spasms which have interfered with exercise are significantly reduced, I am told that I look livelier. My win rate at Solitaire (hand and mind) is up 5 points. And my blood sugar is somewhat reduced. After three months I will have my blood retested and after 6, my vision evaluated. My stamina is notably improved:
(The first day of hyperbaric treatment in Great Neck I was let out of the bus at the bottom of a steep hill with no center in sight. I phoned and they told me to walk up the hill and turn left. That left me in the LIJ hospital parking lot where I questioned a guard only to find that that I had climbed the wrong hill and needed to walk back down again and climb an even steeper hill. It would be fair to say I couldn’t have done that before.)
You can’t smoke anything: a single cigarette or joint during the initial month can knock out the new proliferating cells. And you can’t drink at all for 9 months. They told us of a COPD client who went on a $15,000 bender,wiping out all of his progress. We are to eat a whole food diet high in flavanoids. I have added huperizia and vinoceptine supplements to oxygenate my brain and wear my SomaPulse electromagnetic frequency pulse generator which was designed to proliferate stem cells.
I am still fundraising. I have 40 sessions of hyperbaric oxygen at $200-$250 a pop and they need to be done together, which cuts into my income, I have a Groupon for the first 5, but after that I don’t have the money. This is necessary to cause the stem cells to proliferate.
I am including a link to a tremendous story on stem cells helping a stroke victim, former Redwings hockey player Gordie Howe. This is from a different company, Stemedica Cell Technologies of San Diego, and they injected the cells directly into the spinal fluid which had to take place in Mexico. He got up and walked at once. http://blogs.windsorstar.com/…/howe-makes-phenomenal-recove… Let’s hope this technique gets approved here!
People have been asking how the stem cells go past the blood brain barrier to get to the substantia nigra where dopamine is made. Stem cells are not supposed to be able to cross the BBB, which is why early stem cell treatment for Parkinson’s was not broadly successful.But it seems that the Blood Brain Barrier is less a barrier than a regulator which can at times be selective in what it lets through.Now it isn’t clear to me whether the stem cells actually go through the BBB or just signal cells on the other side but it does appear to make a significant difference clinically. I think they do get through based on the research cited below.
There are three primary sorts of barriers of the BBB, the vascular brain barrier, blood-CSF barrier, and the specialty CNS barriers such as the blood-retinal barrier. They transport molecules in by pores, the opening of tight junctions and receptors. (1) One can also bypass the BBB by going through the nose or injecting directly into the cerebral spinal fluid. This even works for larger molecules like peptides and other proteins.(1) Injecting insulin through the nose has been helpful for Alzheimer’s for instance. And they injected stem cells into the middle turbinate of my nose as one form of administration. It was weird but topical lidocaine prevented pain.
However researchers also found that mannose IV infusions open pores in the BBB and increase enzyme passage 10 fold (2). In fact mannose infusion has become a standalone therapy as well as a way of getting drugs to the brain.
StemGenex, the center that performed my stem cell administration, started using mannose infusions long before they started using intranasal injection. It increased the success for neurological conditions. Their mannose solution increases the diameter of pores for 20 minutes, so it is immediately followed by injected and IV stem cell administration.
If you are academically inclined, the following articles give the science behind getting through the BBB. Our understanding of the BBB is growing every day.
So I had the procedure yesterday. In the morning they took blood and did the mini liposection. I was sedated without loss of consciousness. It was laparoscopic with two tiny incisions, filled with saline and epinepherine then fat cells were extracted. They wrapped my abdomen in a stiff binder and took me to the recovery room. After recovery, while the cells were processed, laser and enzyme activated and mixed with Platelet Rich Plasma, they gave me an infusion of mannose to open the blood brain barrier. Apparently they started this practice before having used the intranasal administration and found great improvement in neurological patients.
The cells came back in a mini IV bag of pink liquid and a group of syringes, one for each of the points we had selected and a catheter for the bladder (the only real painful procedure.) I prevailed upon him to stick me at St. 36 for stamina and he was already using Liver 3 for my toe that has been bursting through the cartilage since the Parkinson’s Walk two years ago.
The IV was somewhat curtailed since I have small veins. The nurse decided that I already had a few billion stem cells, so she drew it out of the IV tube into the syringe. I considered self-injection (and ought to have asked for the doctor to inject more into my chronically stiff neck. )
There is more and the staff was interested in how acupuncture can reduce scars and deal with neurological conditions. The medical director said she was told by a Chinese acupuncturist that acupuncture stimulates the activity of stem cells (albeit at a lower concentration.) Silberstein, M. (2009). The cutaneous intrinsic visceral afferent nervous system: A new model for acupuncture analgesia. Journal of Theoretical Biology, 261(4), 637–642. doi:10.1016/j.jtbi.2009.09.008
I found two exciting pieces of research this week that will affect my treatment. If you have been following me you will know that I am fascinated with the gut bacteria and the other tiny creatures that account for 90% of our DNA. The gut/brain interface is more fascinating than you might imagine!
The first study from the University of Helsinki found that the gut bacteria- the microbiome- of people with Parkinson’s is different than that of healthy people. We have more of some bacteria- which increase the worse the symptoms get and others have gone missing, relatively speaking.
The more Enterobacteriaceae we have, the more severe the symptoms. A lack of Prevotellaceae bacteria in Parkinson’s sufferers could mean these bacteria might have a property which protects their healthy hosts from the disease. This seems strange since I generally consider Prevotellaceae to be a sign of inflammation. Or does this discovery merely indicate that intestinal dysfunction is part of the pathology? It might be a result of Parkinson’s disease.
The second piece of research in Blood, the Journal of the American Society of Hematology, shows that people with more gut bacteria do better with stem cell transplants. The more diverse the microbiome, the better the stem cells take. This of course gets me questioning the pre-op antibiotics that StemGenex recommends. Next stop is sending them the research!
Now given that a healthy gut should have some 10,000 species according to Martin Blaser’s book Missing Microbes and a functioning biofilm, taking a probiotic with a maximum of 13 species of lactobacillis and bifidobacteria isn’t going to make it. I do like to take Saccharomyces boulardii which tends to be under-represented and soil based probiotics for the same reason. And to eat Jerusalem artichokes which help them grow. So I am onto my fermented food regimen which allows for unnamed wild species: full fat unsweetened yogurt from different animal milks, olives, miso of various sorts, blue cheese, kombucha, fermented veggies, kimchee, pickles, refrigerated sauerkraut and raw milk products.