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Why A Parasite Cleanse Can Make You Worse

Black Walnut Hulls

Spring is the time when people often indulge in a seasonal fast.  And since Americans are prone to heroic fasting, many will decide that they should indulge in a parasite cleanse.  Black walnut hulls, wormwood and cloves are traditional, often with a cayenne/fiber supplement.  And the Hulda Clark devotees may use an electric “zapper” to kill parasites.  There are a number of Chinese medicine antiparasite remedies.   But if you have allergies, autoimmune disease or simply a weak immune system, a parasite cleanse can make you worse.

The word “parasite” shows our attitude towards even benign worms (“helminths”) that live in our bodies. We don’t like worms, which we usually only notice if they are in overgrowth.   They are ugly and primitive.   Although only 10% of the cells in our bodies are human, we resist thinking of ourselves as walking colonies in a superstructure.  Commensuals (which merely inhabit us) or Symbionts (which benefit us)  might be better terms.

Of course there are harmful worms which tax our organs or nutrient supply or which burrow into areas where they are dangerous.  Or like pinworms which are itchy and contagious.  But not all worms fit this definition.  And I have long maintained that we most likely have larger organisms along with our probiotic organisms that are necessary to human health.

Some also refer to gut organisms like candida as parasites.  I will speak more about that in another piece, but they are also symbionts that are only problematical in overgrowth.

Most people have heard of the Hygiene Hypothesis which in its most general form shows that children not exposed to dirt and bacteria do not stimulate their immune system enough and are then more vulnerable to disease.  A deeper understanding has other implications.  Our immune system has two major branches (that we know about):  TH1 and TH2.  Parasites and intracellular antigens trigger the TH1 branch of the immune system while extracellular allergens like food allergies, at least some kinds, trigger the TH2 branch.  If your body doesn’t have enough TH1 stimulation, the TH2 may go into overdrive causing autoimmune disease.

However we have seen significant increases in both food allergies and autoimmune systems, so the Old Friends Hypothesis has been put forward, saying that T regulator cells can only become fully effective if they are stimulated by exposure to fairly benign microorganisms and parasites  which have coexisted universally with human beings throughout human history. Examples of organisms that may be important for proper development of  T regulatory cells include lactobacilli, various mycobacteria, and certain helminths.

A recent study demonstrated the impact of worms upon genes responsible for making cytokines that regulate inflammation.  The diseases studied were autoimmune diseases like Crohn’s Disease (72-100% remission) or Ulcerative  Colitis (56%), and allergies like  Celiac Disease (allergy to gluten).  There is early research on heart disease.  Other diseases not yet studied like Lupus, Rheumatoid Arthritis and a variety of other allergies are likely to show similar effects.

There have been a number of studies using the pig whipworm, a kind of roundworm that will live but not reproduce in people.  Eggs are put into a kind of milkshake and are swallowed.  As the worms hatch, the inflammation associated with ulcerative colitis or celiac is significantly reduced.  The American hookworm is used similarly and has shown benefit for asthma.  Neither of these worms is likely to cause disease, increase other parasites, to harm organs or to create other problems.  Some people do have allergies to the pig whipworm and cannot use it (but it is easily killed if that happens).  N. americanus, the species of hookworm used therapeutically, takes on average 0.03ml of blood per day from the host, so anemia is only observed in malnourished individuals with very many hookworms.  Both helminths need to be outside of the body to reproduce so the dosage can be controlled.

Approximately 50% of Americans are believed to have some kind of worm, most of which are benign.  Worms are more prevalent in the South and children who run barefoot in rural areas are more likely to have them, as well as plantation workers and coal miners.  But children in cities and in the north tend to have more autoimmune disease, allergies and asthma.  Nonetheless, hookworms can be troublesome if acquired repeatedly in poorly nourished children or anemic adults.

What we don’t know about allergy and autoimmune disease exceeds what we know by orders of magnitude.  But we do know that humans have evolved with certain parasites and microorganisms like those in the gut bacteria for millions of years.  Having too sterile an environment where we have largely eliminated our benign symbionts along with the bad does increase disease severity.

In Chinese medicine there is the belief that we should all have some of the taint of the environment in order to be able to function within it.  Childhood diseases are  seen in Chinese medicine and western naturopathy as necessary to develop a competent immune system, although many of those have been wiped out due to vaccination.  Parasites are part of the immune stimulation and this has been shown by current western research.  In fact the cardinal sign of imminent death in classical Chinese medicine was that roundworms were leaving the body.

There are a few other cautions to a parasite cleanse that do not have to do with worms.  The aromatic bitters used in typical western cleanses are energetically extremely cold and should not be used long term.

If you run cold, are deficient with low immune reserves or are vegan and you actually have parasite problems, then don’t use a black walnut type cleanse.  It is too cold.    You would probably do better on something like Wu Mei San which is warmer and sour.  Or at least add lots of dry ginger, oregano or prickly ash to warm up the formula.  If you are an excess type who tends to be hot, constipated and red faced with a warming diet, it will be less injurious to your health and digestion.

If you need cleansing, especially long term, then go for a Chinese formula selected for you by a professional who will actually do a TCM diagnosis and select the best one for your pattern, with modifications that fit your particular constitution.  A Chinese formula is balanced to increase your digestive fire, tonify your organs, increase or decrease stomach acid as needed as well as to deal with the parasites.  And the formula will most likely change over time as you change.

The take away from this is that you should not use a parasite cleanse unless you know that you have been infected by parasites that are injurious to your health.  Get a stool test, check for blood anemia and look for symptoms that can be diagnosed.  If you live where constant reinfection is an issue and you are malnourished,  you likely do need a periodic cleanse and you should build up your blood and your gut afterward.

If you have autoimmune disease, asthma or food allergies like gluten sensitivity, you probably shouldn’t do them at all and might investigate the clinical trials that will use benign helminths in a controlled way.  Build up your gut bacteria, heal any inflamed mucosa with slippery elm or marshmallow root tea and then see if parasite therapy will benefit you.  And if you do, don’t forget to report back and let us know how it worked.

See Also:

Our Symbionts Ourselves

Sources:

Wikipedia  Helminthic Therapy

Wikipedia  Hookworm

Wikipedia Hygiene Hypothesis

Wikipedia Gut Flora

Bensky, D. et al.  Chinese Herbal Medicine:  Formulas and Strategies

Fumagalli M, Pozzoli U, Cagliani R, et al. (June 2009). “Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions”. The Journal of Experimental Medicine 206 (6): 1395–408. doi:10.1084/jem.20082779. PMID 19468064

David E. Elliott; Robert W. Summers; Joel V. Weinstock. (2005). “Helminths and the Modulation of Mucosal Inflammation”. Current Opinion in Gastroenterology 21 (2): 51–58. PMID 15687885

Fumagalli M, Pozzoli U, Cagliani R, et al. (June 2009). “Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions”. The Journal of Experimental Medicine 206 (6): 1395–408. doi:10.1084/jem.20082779. PMID 19468064

Magen E, Borkow G, Bentwich Z, Mishal J, Scharf S (2005). “Can worms defend our hearts? Chronic helminthic infections may attenuate the development of cardiovascular diseases”. Med. Hypotheses 64 (5): 904–9. doi:10.1016/j.mehy.2004.09.028. PMID 1578048

Hadley C (2004). “Should auld acquaintance be forgot.”. EMBO Rep. 5 (12): 1122–4. doi:10.1038/sj.embor.7400308. PMID 15577925

Aziz, R.  The Case for Biocentric Microbiology.  Gut Pathogens

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Grow Your Own Drugs

It is almost Spring, depending on where you are in the country.  Time to start the annuals and to awaken the garden.  Even if your garden is primarily ornamental, you can include medicinal herbs, many of which are lovely.  And don’t forget to eat the weeds, once you know what they are and what is safe!          Continue reading Grow Your Own Drugs

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What is More Dangerous, Herbs or CT Scans?

Do you think  politicians or even the FDA could answer this question, posed by my friend Alan Tillotson?

Fact A :  Herbs, vitamins and nutritional supplements caused zero deaths in 2008 [in most years actually]

Fact B:  CT scans cause 30,000 new cancers and 14,500 deaths each year, with children being most at risk

Which of these answers is the correct political action to take?

A. We should crack down on the supplement industry

B. We should crack down on the CT scan industry

Continue reading What is More Dangerous, Herbs or CT Scans?

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How to Make Burn Cream

Zi gen Lithospermum

Burn cream, known as purple cloud ointment or shiunko in Japanese medicine is traditionally used under direct moxa where small “rice grain” cones are adhered to the body with the purple cream.  But it is also used for burns, skin rashes, psoriasis and eczema.
The major herb used in the burn cream is lithospermum, also known as gromwell or puccoon, or in pinyin Chinese as  Zi cao gen (purple herb root). Lithospermum is in the category of herbs that cool fire toxins, Continue reading How to Make Burn Cream

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February/March Herbal Blog Party: Emerging From Winter With Herbs

Kitty in Spring Snow by Peter Pateau

The herbal blog party for this month deals with herbs that help us emerge from Winter, making the transition into Spring.  For me the promise awakens when the angle of bright sunlight changes to hit my back window, where buildings have blocked it all winter.  The raised beds in the back may soon lose their snow so that the Jerusalem artichokes, anise hyssop and calamus can poke through.  Meanwhile my sister in Seattle is surrounded by a riot of hyacinths and Rosie in Houston frets that she won’t have time to harvest the cleavers before the hot temperatures wipe them out.

We are writing from different places, with different climates and different experiences.  But the awakening of Spring stirs something in each of us.  And we make our preparations, whether from a Lenten fast, a week-long cleanse or just the venture out to harvest the wild greens we have been craving.

LadyBarbara wrote Rising Spring about the quickening of the season and how she changes her diet for that new movement.

Yael Grauer wrote Emerging from Winter With Herbs about her three favorite adaptogens and nasal irrigation.

Rosalee de la Foret wrote about Spring violets, Emerging from Winter to Find Violet

Emerging rhubarb

Sean Donohue wrote Skunk Cabbage: New England Bear Medicine about the plant that heats its way up through the snow and feeds the bears after the acorns are gone.

Granny Sam Gahagan writes from her snow covered lair about Emerging from Winter in the Appalachians.  (You westerners might not know that we still have winter, with more storms to come- makes it a bit hard to get into the Spring spirit when you have to dig the chickweed from under the snow.)

Karen Vaughan writes about Nettles! her favorite spring herb, and year long food.  Whether eaten, drunk or flogged on the skin, nettles stir up your vitality.

April Moonflower, at Red Clover Mamma wrote about Herbs and Essential Oils for Emotional Detoxing

Sarah Head has a beautifully insightful post on Emerging from Winter With Herbs, focusing on the emotional side.  Stunning photographs.

Stefan Chemlik,  writes Emerging from Winter with a Chinese medicine point of view, focusing on the Liver.  Scroll down to to his list of things you can do to clean up your act under Feeling fat, fuddled or fatigued?

Feel free to copy this list to your website, and please visit the sites of the contributors.  I love reading the different approaches our passionate herbalists have to this.

And see the UK Herbarium blog party on the same topic on Elizabeth Marsh’s Apotheblogary.

A special thanks to all participants and readers, and to Herbwifery.org, where the herbal blog parties were born!

Photography credits:

fishwrapper.wordpress.com/2008/04/,

letterfromhere.blogspot.com/2009/03/tiptoeing-through-tulips-after-madisons.htm

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Nettles!

Stinging Nettles: Urtica dioica

“If they would drink nettles in March
and eat mugwort in May
fewer young ladies
would go to the grave”
- in John Murrell, A Garden of Herbs, 1621

Nettles are the quintessential herb for getting over winter in my book.  They push their way up in early spring, despite a dusting of snow.  The small ones are bright and vital and don’t have quite the sting to them. But their roots mine the soil for minerals, often Continue reading Nettles!

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Limit Carbohydrates Rather Than Fats To Prevent Heart Disease

A new study by  Siri-Tarino of the Children’s Hospital Oakland Research Institute in California,concluded in the American Journal of Clinical Nutrition that we are missing lower cardiovascular disease targets when we urge the obese to lower dietary fats.  The emphasis on reducing dietary saturated fat isn’t preventing cardiovascular disease (CVD) in the obesity epidemic and associated metabolic disturbances, the authors concluded.
Continue reading Limit Carbohydrates Rather Than Fats To Prevent Heart Disease

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So You Think Surgery is a Good Way To Lose Weight?

Like many people dealing with weight problems I have looked into surgery as a way of losing weight. It seems so inviting to have a quick fix and I saw medical studies indicating that bariatric (weight loss) surgery was the only way to permanently lose weight. And yet all of my patients who had surgery, from a Roux en Y gastric bypass to Lap Bands have had complications. And all but one, whose Lap Band is too new to tell, are still obese.

Continue reading So You Think Surgery is a Good Way To Lose Weight?

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Meta-Study Finds Acupuncture Eases Menstrual Pain

A Korean meta-study reviewing data from 27 studies found that acupuncture was effective in relieving menstrual pain. Over 3000 women were studied in total, with treatments ranging from Traditional Chinese Medicine to herbal injections into acupuncture points.  The analysis  from Kyung Hee Medical Center found that patients with severe period pain reported a greater reduction in their symptoms when using acupuncture than when using pharmacological treatments.

Acupuncture could help period pain, researchers say

Stomach ache

Period pain is a common complaint

Acupuncture may be an effective way of easing severe period pain, a South Korean review of 27 studies suggests.

Researchers said there was “promising evidence” for acupuncture in treating cramps, but that more work was needed.

More at:

http://news.bbc.co.uk/2/hi/health/8518745.stm

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Niacin Outperforms Drug At Cholesterol Lowering

In a study published in the New England Journal of Medicine, a time release version of an inexpensive Vitamin B (Niacin- not niacinamide) was compared to a common cholesterol drug, ezetimibe (trade name Zetia), made by Merck.  The vitamin gave superior results.

Continue reading Niacin Outperforms Drug At Lowering Cholesterol

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Home Remedy to Use Instead of Nyquil

This amusing video shows a homemade substitute for Nyquil, which contains a number of  ingredients you might not want to put into your body.  His uses Southern Comfort as the alcohol, but if you click through to Vimeo there are a number of comments with other home remedies.  I prefer to use either Thieves’ Vinegar or honey, fresh garlic and ginger syrup.  Or a drop or two of essential oil of rosemary over the glands and at the nape of the neck.

KniQuil from Hot Knivez on Vimeo.

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What Does Research Say About Eating Meat?

Meat and Vegetables

We are badly in need of a study that compares good vegetarian to good meat-containing diets using quality foods, with high vegetable content and good quality fats in both diets. Too often vegetarians are compared to a standard American population, health-conscious vegans are compared to non-health conscious omnivores and studies on omnivores with low meat diets are extrapolated to suggest that a diet with no animal food altogether may be superior. The study should isolate the effects of gluten from other starchy foods and meats from fish. Continue reading What Does Research Say About the Health of Eating Meat?

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High BMI Kids Not Necessarily Fat

A recent large study of children with high body mass indexes (BMI) found that many children of normal body mass had high fat percentages while 25% of children with high BMI were not obese by fat percentage criteria.

BMI (weight in kilograms divided by height in meters squared) does not distinguish between the weight of muscle, fat or bone and has a statistical artifact that tends to classify tall children as overweight. Continue reading Kids with High Body Mass Index Not Necessarily Fat

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Cordyceps Investigated for Cancer Drug

Cordyceps ophioglossoides

Cordyceps sinensis has been part of my anti-cancer formulas for many years, since Thai doctor Santi Rosswong suggested that I add it to my reishi formulas for stamina.  It appears from recent research that the herb stops cell proliferation as well.

Cordyceps is a strange herb, a fungus that colonizes then kills an insect, as shown in a BBC  video (with one of the other 680 described cordyceps species found on 6 continents.)  When the Cordyceps sinensis fungus attacks a Continue reading Cordyceps for stamina, against cancer

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Communication In A Persistent Vegetative State?

A recent New York Times article found that by using functional MRIs on long term persistent vegetative state patients, a few could hear and process information.  The idea sounds exciting, helping differentiate those who had residual brain function from the majority that did not.  But a few caveats are in order: Continue reading Communication In A Persistent Vegetative State?

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Agave Nectar A Healthy Sweetner?

When Agave nectar first burst on the scene as a healthier sweetener, it appeared to be superior to sugar and other dietary sweeteners like high fructose corn syrup.  It was easy to imagine that for thousands of years Native Americans had been tapping the sap of the agave plant, Continue reading Agave Nectar: A Healthy Sweetner?

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More Problems With Paxil

I just wrote a piece on how Paxil (paroxetine) can cause serious birth defects, shown when independent Swedish researchers reanalyzed data from the manufacturer.  Now new information shows that it, along with imipramime, does no better than a placebo at helping depression. Continue reading More Problems With Paxil

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Going Gluten and Dairy Free

What can I eat?   Don’t worry, this is a normal reaction upon hearing that you should give up dairy and gluten.  And it takes planning, and a shift in what you think is good to eat.

Allergy tests have extremely high rates of false Continue reading Going Gluten and Dairy Free

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Fermented Blueberry Drink Prevents Diabetes and Obesity

For some time I have been promoting probiotic foods (foods with “good bacteria” for the gut) as superior to probiotic pills.  The probiotics in food are present with their prebiotic food sources, often have fat or other compounds to protect them from digestive juices and are found in the forms that our bodies evolved to expect.  Now a study from the University of Montreal shows that fermented blueberry juice, using the organisms that are found on Continue reading Fermented Blueberry Drink Prevents Diabetes and Obesity

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247 Hospital Patients Die Daily Due to Doctor's Not Washing their Hands

If I were in the hospital, I would make sure to have a waterless hand sanitizer made with essential oils in a pump by my bed.

Over the last 30 years, despite countless efforts at change, poor hand and clothing hygiene has Continue reading 247 Hospital Patients Die Daily Due to Doctor’s Not Washing their Hands

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