Tag Archives: Oxygen

How Long Does it Take After a Stem Cell Implant to See Results?

Diseases and conditions where stem cell treatm...
Diseases and conditions where stem cell treatment is promising or emerging. (See Wikipedia:Stem cell#Treatments). Bone marrow transplantation is, as of 2009, the only established use of stem cells. Model: Mikael Häggström. To discuss image, please see Template talk:Häggström diagrams (Photo credit: Wikipedia)

How long does it take before I will see the results of the stem cells? The short answer is that it varies considerably, as stem cell proliferation and concentration increases.

One woman in my group was so pleased with the turnaround in her  30 year MS that she came back for more, In her first treatment she had absolutely no improvement for 6 months, when all of a sudden she could raise her leg two feet instead of two inches. She subsequently went from not being able to turn over in bed to being able to drive herself to the gym and work out and she has retained her improvements for several years. But she went through the treatment with another woman with longstanding MS whose improvements mostly happened the first month.

So far my improvements are subtle. My foot spasms which have interfered with exercise are significantly reduced, I am told that I look livelier. My win rate at Solitaire (hand and mind) is up 5 points. And my blood sugar is somewhat reduced.  After three months I will have my blood retested and after 6, my vision evaluated. My stamina is notably improved:

(The first day of hyperbaric treatment in Great Neck I was let out of the bus at the bottom of a steep hill with no center in sight. I phoned and they told me to walk up the hill and turn left. That left me in the LIJ hospital parking lot where I questioned a guard only to find that that I had climbed the wrong hill and needed to walk back down again and climb an even steeper hill. It would be fair to say I couldn’t have done that before.)

You can’t smoke anything:  a single cigarette or joint during the initial month can knock out the new proliferating cells.  And you can’t drink at all for 9 months.  They told us of a COPD client who went on a $15,000 bender,wiping out all of his progress.  We are to eat a whole food diet high in flavanoids.  I have added huperizia and vinoceptine supplements to oxygenate my brain and wear my SomaPulse electromagnetic frequency pulse generator which was designed to proliferate stem cells.

I am still fundraising. I have 40 sessions of hyperbaric oxygen at $200-$250 a pop and they need to be done together, which cuts into my income, I have a Groupon for the first 5, but after that I don’t have the money. This is necessary to cause the stem cells to proliferate.

I am including a link to a tremendous story on stem cells helping a stroke victim, former Redwings hockey player Gordie Howe. This is from a different company, Stemedica Cell Technologies of San Diego, and they injected the cells directly into the spinal fluid which had to take place in Mexico. He got up and walked at once. http://blogs.windsorstar.com/…/howe-makes-phenomenal-recove… Let’s hope this technique gets approved here!

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Getting Through the Blood Brain Barrier

BBB and nose limbic systemPeople have been asking how the stem cells go past the blood brain barrier to get to the substantia nigra where dopamine is made. Stem cells are not supposed to be able to cross the BBB, which is why early stem cell treatment for Parkinson’s was not broadly successful.But it seems that the Blood Brain Barrier is less a barrier than a regulator which can at times be selective in what it lets through.Now it isn’t clear to me whether the stem cells actually go through the BBB or just signal cells on the other side but it does appear to make a significant difference clinically.  I think they do get through based on the research cited below.

 There are three primary sorts of barriers of the BBB, the vascular brain barrier, blood-CSF barrier, and the specialty CNS barriers such as the blood-retinal barrier.  They transport molecules in by pores, the opening of tight junctions and receptors. (1) One can also bypass the BBB by going through the nose or injecting directly into the cerebral spinal fluid. This even works for larger molecules like peptides and other proteins.(1) Injecting insulin through the nose has been helpful for Alzheimer’s for instance. And they injected stem cells into the middle turbinate of my nose as one form of administration. It was weird but topical lidocaine prevented pain.

BBB and junctions
Ways through the Blood Brain Barrier

However researchers also found that mannose IV infusions open pores in the BBB and increase enzyme passage 10 fold (2). In fact mannose infusion has become a standalone therapy as well as a way of getting drugs to the brain.

StemGenex, the center that performed my stem cell administration, started using mannose infusions long before they started using intranasal injection. It increased the success for neurological conditions. Their mannose solution increases the diameter of pores for 20 minutes, so it is immediately followed by injected and IV stem cell administration.

English: The Blood Brain Barrier and Astrocyte...
English: The Blood Brain Barrier and Astrocytes type 1 (Photo credit: Wikipedia)

If you are academically inclined, the following articles give the science behind getting through the BBB. Our understanding of the BBB is growing every day.

 

 

And if you would be so kind as to help fund my Parkinson’s stem cell transplant: http://www.gofundme.com/eg4ymk

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